Pizza Roll Stuffed Garlic Knots

Featured in: Weekend Farmhouse-Style Treats

These irresistible garlic knots start with a simple two-ingredient protein dough that's incredibly easy to work with. Each knot is rolled into a strip, filled with savory pepperoni and melted mozzarella, then tied into a classic knot shape. The magic happens in the oven when they're brushed generously with garlic butter halfway through baking, then finished with another coat when they emerge golden and fragrant.

The result is a soft, pillowy exterior with a gooey, cheesy center that's packed with Italian flavors. Perfect for game day, parties, or as a satisfying snack alongside your favorite dipping sauce.

Updated on Sun, 08 Feb 2026 08:09:00 GMT
Golden-brown Pizza Roll Stuffed Garlic Knots fresh from the oven, brushed with garlic butter and herbs, served on a rustic wooden board. Pin This
Golden-brown Pizza Roll Stuffed Garlic Knots fresh from the oven, brushed with garlic butter and herbs, served on a rustic wooden board. | orchardflint.com

My roommate challenged me to make something that tasted like pizza but used Greek yogurt dough, and honestly, I thought she was out of her mind. But then I tied that first knot, brushed it with garlic butter, and the smell that came out of the oven made her forget all about her skepticism. These pizza roll stuffed garlic knots became the thing I make when I need to impress people without spending hours in the kitchen. They're soft, they're savory, and somehow they manage to feel both indulgent and surprisingly light.

I brought these to a game night once, and they disappeared faster than the snacks I'd carefully cubed and arranged on a board. Someone asked if I'd ordered them, which was the best compliment I could've gotten. Now when friends ask what they can bring to gatherings at my place, I just say these knots, and everyone knows exactly what I mean.

Ingredients

  • Self-rising flour (1 ¼ cups): This is your shortcut to tender knots without dealing with yeast and rising times; it already has the leavening built in.
  • Nonfat Greek yogurt (1 cup): The secret to structure and protein content, and the moisture in the yogurt replaces what oil or eggs would normally provide.
  • Salt (½ tsp for dough): Brings out the flavor of the yogurt and flour, keeping the dough from tasting bland.
  • Pepperoni slices (18 slices): Use good quality pepperoni because those crispy edges will get even more flavorful in the oven, and cheaper slices tend to become rubbery.
  • Shredded mozzarella cheese (¾ cup): Melts beautifully and creates pockets of richness inside each knot without overwhelming the dough.
  • Unsalted butter (3 tbsp melted): Allows you to control the salt in the garlic butter and ensures the knots get that golden, crispy exterior.
  • Garlic cloves (2 finely minced): Fresh garlic matters here because the oil releases when heated, coating every inch of the knot with fragrance.
  • Fresh parsley (1 tbsp chopped): Adds brightness and a pop of color that makes these look homemade in the best way.
  • Parmesan cheese (2 tbsp grated, optional): The optional garnish that actually shouldn't be optional because it adds a salty umami finish.

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Instructions

Heat your oven and prep your workspace:
Get your oven to 400°F and line a baking sheet with parchment paper so nothing sticks and cleanup is effortless.
Make the dough come alive:
Combine flour, Greek yogurt, and salt in a bowl and stir until everything starts clinging together, then knead it gently for just a couple of minutes until it's smooth and cooperative. This dough doesn't need aggressive kneading; treat it like you're getting acquainted with it, not wrestling it into submission.
Divide and shape into ropes:
Split the dough into 12 even pieces and roll each one into a rope about 7 inches long, using the heel of your hand to keep them consistent. If the dough springs back, let it rest for a minute and try again.
Flatten for filling:
Take each rope and gently press it into a strip about 1.5 inches wide, creating a canvas for your filling. The edges will be slightly thinner than the center, which is exactly what you want.
Layer in the pizza magic:
Along the center of each strip, lay down 1-2 slices of pepperoni and a small mound of mozzarella, being careful not to overstuff or the seams will burst open during baking.
Roll and seal:
Carefully roll each strip lengthwise like you're tucking in a burrito, pressing the seam firmly so nothing leaks out in the oven. You'll feel a little satisfying click when the cheese and pepperoni are fully enclosed.
Tie the knot:
Take your filled rope and tie it into a loose knot, tucking the ends underneath so it holds its shape. It doesn't need to be perfect; the beauty is in the rustic, handmade look.
Arrange on the sheet:
Place each knot seam-side down on your parchment-lined baking sheet, giving them a little space so the heat can circulate.
Make the garlic butter coating:
Whisk together melted butter, minced garlic, parsley, and salt in a small bowl until the garlic is evenly distributed. The smell at this point is basically edible.
First butter brush:
Brush half of the garlic butter over the knots before they go in the oven, making sure to get into any crevices.
Bake until golden:
Slide them into the oven for 16-18 minutes until they're deeply golden brown and cooked through. You'll smell the garlic intensifying as they bake.
Finish with remaining butter and cheese:
Pull them out, brush with the remaining garlic butter while they're still hot so it soaks in, then scatter Parmesan on top if you're using it. The residual heat will make the cheese slightly golden.
Serve and enjoy:
Let them cool for just a minute or two so the cheese sets slightly, then serve warm with marinara for dipping if you want.
Golden Pizza Roll Stuffed Garlic Knots on a white plate, revealing melted mozzarella and pepperoni filling, with a small bowl of marinara sauce. Pin This
Golden Pizza Roll Stuffed Garlic Knots on a white plate, revealing melted mozzarella and pepperoni filling, with a small bowl of marinara sauce. | orchardflint.com

There was a moment during a particularly stressful week when I made a batch of these at midnight just because I needed to do something with my hands that had an immediate, delicious reward. By the time they came out of the oven, my mood had completely shifted. Food can do that sometimes—turn a rough moment into something warm and manageable.

The Greek Yogurt Dough Secret

This dough is a game changer if you've never worked with Greek yogurt as a base. The proteins in the yogurt create structure without needing eggs, and the lactic acid makes everything taste slightly tangy in a way that plays beautifully against the salty pepperoni and cheese. I've tried making these with regular doughs that require rising time, and honestly, this one tastes better because the yogurt adds a subtle richness that store-bought dough just can't match.

Customizing Your Filling

While pepperoni and mozzarella are the classic combo, these knots are honestly flexible. I've made vegetarian versions by roasting thin slices of zucchini and red pepper, then layering them in with the cheese for something lighter. The dough is neutral enough that it works with whatever filling speaks to you, and the garlic butter coating ensures they still taste phenomenal.

Storage, Freezing, and Reheating

These keep beautifully, which is why I often make a double batch and freeze half for later. Store cooled knots in an airtight container in the fridge for up to three days, or freeze them on a baking sheet before transferring to a freezer bag where they'll last a month. Reheat straight from frozen in a 350°F oven for about 12 minutes until they're warm through and the outside is crispy again.

  • Frozen knots often taste better after reheating than room-temperature ones because the gentle heat revives the texture.
  • If you're in a hurry, you can eat these cold too, though they're absolutely best served warm and the melted cheese inside is part of the whole experience.
  • Make these the night before a gathering and you'll have an impressive appetizer that requires almost zero last-minute effort.
Freshly baked Pizza Roll Stuffed Garlic Knots arranged on a cooling rack, showcasing soft dough and golden edges, ready to serve as a party snack. Pin This
Freshly baked Pizza Roll Stuffed Garlic Knots arranged on a cooling rack, showcasing soft dough and golden edges, ready to serve as a party snack. | orchardflint.com

These knots turned out to be the recipe I make most often, not because they're fancy, but because they're the right balance of simple and impressive. Every time, they remind me why I love cooking in the first place.

Recipe FAQs

Can I make the dough ahead of time?

Yes, you can prepare the dough up to 24 hours in advance. Wrap it tightly in plastic wrap and refrigerate. Let it come to room temperature for about 15 minutes before rolling and stuffing, as cold dough may be more difficult to shape.

What other fillings work well?

Beyond pepperoni, try cooked Italian sausage, sautéed mushrooms and spinach, or sun-dried tomatoes with fresh basil. For a vegetarian option, layers of roasted vegetables and herbs create delicious results. Just ensure any filling is well-drained to prevent sogginess.

Can I freeze these before or after baking?

Both methods work! Freeze uncooked knots on a baking sheet until firm, then transfer to a freezer bag for up to 3 months. Bake from frozen, adding 2-3 minutes to the cooking time. Already-baked knots freeze well too—reheat in a 350°F oven for 5-7 minutes.

Why use Greek yogurt in the dough?

Greek yogurt combined with self-rising flour creates a surprisingly soft, pliable dough that's higher in protein than traditional versions. The acidity in yogurt also helps tenderize the gluten, resulting in knots that stay soft and don't become tough or rubbery.

How do I prevent the filling from leaking during baking?

Pinch the seam tightly after rolling each strip, and place knots seam-side down on the baking sheet. Don't overfill—too much cheese will escape. A light coating of garlic butter before baking also helps seal the exterior. Some minimal cheese melting out is normal and adds to the appeal.

Can I use regular flour instead of self-rising?

For every cup of all-purpose flour, add 1 ½ teaspoons baking powder and ¼ teaspoon salt. Whisk thoroughly before combining with the yogurt to ensure even distribution of leavening agents throughout the dough.

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Pizza Roll Stuffed Garlic Knots

Soft garlic knots stuffed with pepperoni and cheese, brushed with buttery garlic glaze

Time to Prep
20 minutes
Time to Cook
18 minutes
Overall Time
38 minutes
Created by Luke Campbell


Skill Level Easy

Cuisine Type American-Italian

Makes 12 Portions

Dietary Details None specified

What You’ll Need

Protein Dough

01 1 1/4 cups self-rising flour
02 1 cup nonfat Greek yogurt
03 1/2 teaspoon salt

Filling

01 18 slices pepperoni
02 3/4 cup shredded mozzarella cheese

Garlic Butter

01 3 tablespoons unsalted butter, melted
02 2 cloves garlic, finely minced
03 1 tablespoon fresh parsley, finely chopped
04 1/4 teaspoon salt

Garnish

01 2 tablespoons grated Parmesan cheese

Step-by-Step Guide

Step 01

Prepare oven and baking surface: Preheat oven to 400°F. Line a baking sheet with parchment paper.

Step 02

Mix dough components: In a mixing bowl, combine self-rising flour, Greek yogurt, and salt. Stir until a shaggy dough forms, then knead gently until smooth, approximately 2 to 3 minutes.

Step 03

Portion dough: Divide dough into 12 equal pieces. Roll each piece into a 7-inch rope.

Step 04

Flatten dough strips: Flatten each rope into a strip approximately 1.5 inches wide.

Step 05

Fill strips: Place 1 to 2 slices of pepperoni and a small mound of mozzarella along the center of each strip.

Step 06

Seal filling: Carefully roll up the strip lengthwise to encase the filling, pinching the seam to seal.

Step 07

Form knots: Tie each filled rope into a loose knot and tuck the ends underneath.

Step 08

Arrange on baking sheet: Arrange knots on the prepared baking sheet with seam side down.

Step 09

Prepare garlic butter: In a small bowl, mix melted butter with minced garlic, parsley, and salt.

Step 10

Apply initial butter coating: Brush half the garlic butter over the knots.

Step 11

Bake: Bake for 16 to 18 minutes, until golden brown and cooked through.

Step 12

Apply finishing touches: Remove from oven, brush with remaining garlic butter, and sprinkle with Parmesan cheese if desired.

Step 13

Serve: Serve warm, optionally with marinara sauce for dipping.

Needed Gear

  • Mixing bowl
  • Measuring cups and spoons
  • Baking sheet
  • Parchment paper
  • Pastry brush

Allergy Advisory

Review all ingredients for allergens. Check with a health expert if you have concerns.
  • Contains wheat and gluten
  • Contains milk and dairy products
  • May contain eggs in processed pepperoni
  • Verify pepperoni and cheese labels for additional allergen information if sensitive

Nutrition Details (per portion)

This data is provided for your reference. Always consult with a healthcare professional for nutrition advice.
  • Caloric Value: 120
  • Fats: 6 grams
  • Carbohydrates: 11 grams
  • Proteins: 7 grams

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